Posted by Conundrum on November 20, 2010, at 10:37:15
In reply to Re: 7 days, posted by morgan miller on November 16, 2010, at 13:26:00
I tend to think there might be a synergy going on when you combine 5 HT2C antagonism and serotonin reuptake inhibition. Taking low dose prozac does both and gets me motivated. Taking remeron does the antagonism but poops out for me. I think the 5 HT1A activation, and perhaps some of the other serotonergic receptors getting hit, helps increase the norepinephrine and dopamine disinhibition of
5 HT2C antagonism and keeps it from pooping out perhaps.> >If this trend continues, I'll consider going off Paxil to see how agomelatine works on its own. So far so good.
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> Are you concerned that there is some synergy here and you may not feel as well on Paxil? I'm always worried that if drugs like SSRIs work and I stop them, they may not work as well when I try to get back on them. If you don't have any unwanted side effects from Paxil, I would not get off it.
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> I'm guessing Paxil has given you the most benefit of all the SSRIs and you have given them all a good shot.
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Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual dysfunction. )
Country:USA
Currently taking mirtazapine, tianeptine, and SAM-e
poster:Conundrum
thread:968721
URL: http://www.dr-bob.org/babble/20101117/msgs/970837.html