Posted by sigismund on November 11, 2010, at 1:04:22
In reply to Re: Day 1 on ago » sigismund, posted by orbital on November 10, 2010, at 14:37:07
>> Your body will likely end up needing quite enough of this chemical.
>What do you mean by this?
When I look back I realise I could have saved myself some difficult afternoon anxiety if I had gone up more slowly. Eventually I had no problem taking high doses but why give yourself a hard time to get a tolerance?
>Have you noticed an increased response to a higher agomelatine dose?
Not so much to higher doses as such, but yes, that too.
What I noticed was initially a calm nice feeling followed after some weeks by the afternoon anxiety which was quite unlike normal anxiety and was a product of the 5ht2c antagonism leading to higher NE maybe. This passed after maybe a month? I could have avoided the whole thing, I now realise.