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Re: Who has taken an NRI long-term??

Posted by ggggg123 on November 7, 2010, at 16:24:05

In reply to Re: Who has taken an NRI long-term?? » Conundrum, posted by ed_uk2010 on November 7, 2010, at 15:53:08

The fact is norepinephrine is a very important neurotransmitter in the brain, without it you won't feel normal, hence you will have some kind of "depression" Experts say this can be caused due to a complete lack of norep and/or serotonin, or it can be caused by an abnormal ratio, hence too much serotonin too little NE due to ssri use. Either way the right balance needs to be restored to feel normal. Venlafaxine could be a good option, in high doses for people who are termed treatment resistant, it is the gold standard here in the uk and is regularly used on the psych ward. I may try it but, the problem is i will feel like crap till i get to the high doses. I imagine reboxetine works very quick like wellbutrin, this way we start to feel better quicker and can concentrate on recovering rather than going through weeks of hellish side effects, like with the ssri's.


I will go with which ever med the doc agrees on prescribing, probably with reboxetine number one followed by the most noradrenergic tca.


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