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Re: gene therapy for depression, how far are we away?!

Posted by Conundrum on November 1, 2010, at 11:14:23

In reply to Re: gene therapy for depression, how far are we away?!, posted by SLS on November 1, 2010, at 5:03:13

> > Wow thats a great article. It was interesting where it said the brain can produce all the serotonin it wants,
>
> p11 is actually a gene. It directs the activity of the neurotransmitter reuptake molecule so that it is incorporated into the cell membrane in such a way so as to make it available for synaptic neurotransmitter to bind to and be transported back into the neuron. In the absence of p11, the transporter is ineffectual.
>
>
> - Scott

So without the p11 gene, the reuptake of serotonin in to the cell is disrupted. Geez that doesn't sound at all familiar. Now fixing this is supposed to help with depression, when drugs do the opposite?


Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual dysfunction. )
Country:USA
Currently taking mirtazapine and tianeptine

 

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URL: http://www.dr-bob.org/babble/20101030/msgs/967924.html