Posted by SLS on May 2, 2009, at 8:01:36
In reply to Re: OCD - Just a thought. » yxibow, posted by SLS on May 2, 2009, at 7:20:18
> Recent research seems to be focusing on the evolution of hyperactive dopaminergic circuitry loops in the basal ganglia (cortico-striato-thalamic) that are allowed to occur due to a deficit of serotonergic modulation afferent from the raphe nuclei. There appears to be no interest in the locus coeruleus or noradrenergic pathways.
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> Do neuroleptics help at all?
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> - Scott
Recent research seems to be focusing on the formation of circular loops that run on and on and on. These loops use dopamine as their primary neurotransmitter. These brain circuits are located in an area of the brain called the basal ganglia. More specifically, imaging techniques have isolated these looping circuits to comprise areas of the brain known as the cerebral cortex, striatum, and thalamus. Normally, the level of activity in these areas are regulated by serotonin coming from another structure of the brain known as the raphe nuclei. Without enough serotoninergic control to suppress the dopamine neurons, they are allowed to become hyperactive and form endless loops.Do antipsychotics that block dopamine receptors help at all?
Better?
:-)
- Scott
poster:SLS
thread:893777
URL: http://www.dr-bob.org/babble/20090426/msgs/893856.html