Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Dopamine raises + NE reuptake = worsing SAD ??

Posted by desolationrower on March 4, 2009, at 6:22:44

In reply to Re: Dopamine raises + NE reuptake = worsing SAD ?? Michael Bell, posted by Vincent_QC on March 2, 2009, at 7:11:17

ok some misunderstandings here

there is a difference between 'lowering' a neurotransmitter and blocking the receptor for a neurotransmitter, as well as affecting the neurones. for example, nris reduce LC firing, but incraease NA levels several hundred percent, and don't block the receptor (well, some tcas block alpha1 adreoceptors)

"MAOI's : They raises the level of the SE, NE and DA as well as bloking some others things like the alpha1 blockade, D2 blockade, H1 blockade, muscarinic blockade and 5HT2 blockade ..."

no MAOIS availible (or created, afaik) block any of those receptors

i do think its worth trying to differentiate between paranoia and non-paranoid social anxiety. the odd/eccentric personality diorders are commonly comorbid with avoidant personality, but remember schizophrenia in general is hypodopaminergic in the pfc, so even there antipsychotics aren't great, and NRIs could be helpful.

i woudl like to see the full study, its hard to compare to the old one with just an abstract, but i think it just shows the way DSM categories f*ck up research.





Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:desolationrower thread:883142