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Re: new study finds no D2 dopamine abnormality in mav27

Posted by Michael Bell on March 1, 2009, at 2:50:04

In reply to Re: new study finds no D2 dopamine abnormality in SP, posted by mav27 on March 1, 2009, at 0:22:58

The previous study that did find an abnormality is here: http://ajp.psychiatryonline.org/cgi/content/full/157/3/457

As far as which study is the accurate one, it is hard to say. There certainly is a dysfunction of the dopamine and serotonin system, but just increasing the level of a neurotransmitter probably won't cut it. Likely there is an allele variation that affects many of the neurotransmitters and neuropeptides in the brain, in specific portions of the brain. However, there seems to be some headway with genetic scanning. Here's a study that directly links differences in serotonin allele's with social reward and social anxiety:

http://www.medicinenet.com/script/main/art.asp?articlekey=95773

Here's another recent study that shows that there are differences between social phobes and non-phobic people as far as the dopamine and serotonin transporters (as opposed to receptors)are concerned:

http://jnm.snmjournals.org/cgi/content/abstract/jnumed.107.045518v1?ck=nck


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poster:Michael Bell thread:883142
URL: http://www.dr-bob.org/babble/20090223/msgs/883170.html