Posted by llurpsienoodle on July 29, 2008, at 16:01:58
In reply to Re: 2 days' worth of experimentation » llurpsienoodle, posted by yxibow on July 29, 2008, at 2:08:54
> > Day 1) glass of wine at 7pm & sonata at 10:30 pm
> > woke up at 5:00 am, stayed in bed until 5:30 am. Felt in a daze all day long. Kind of tired, but caffeine stimulated.
>
> Okay -- here's where stacking sleep agents is a BAD thing. The half life of alcohol, for a female, I believe you are, but I could be mistaken, would still be in you when you took the Sonata. Not a good thing.
Yep, I am a woman. A giant woman, but still female. :)>
> Sonata is fairly weak though as a sleep agent for most people.
>It has such a short half-life, that's why I think that I can't stay asleep past 3-5am
>
> > Day2) klonopin at 4pm & zolpidem at 10:30 pm. Woke up at 5, fell back asleep. woke up at 6, fell back asleep, got up at 7am. I feel groggy, but hopefully a cup of coffee can pull me back into the realm of the living undead.
>
>
> Here we have an example of why Ambien won't work if you're taking Klonopin regularly. The pseudobenzodiazepine agents are fairly useless if you are already taking a benzodiazepine as they eventually all act on the sleep receptor of GABAa.
>I wonder how much benzo usage it takes to downregulate the brain's natural production/response to GABA? I was off of klonopin for several weeks. Maybe 4-6 weeks? Then my mom came to visit :(
>
> And yes, things have to be tried more than one time. But I can't emphasize enough that stacking sleep agents can get one into real trouble -- the desire to sleep leading to oh, well, I'll take a benadryl with some Ambien and.... yes, respiratory depression, coma, etc.((((yxibow))))) thank you for your concern. I will try to be more careful
>
>
> Of all the agents though, I guess I would either go for the Ambien or the Sonata. Habituation occurs much faster with any benzodiazepine.
>okay- good to know
>
> It's not an "easy question". Sleep regulation is a hard thing, trust me, I have been through multiple agents. But then again -- everyone is different. I'm just saying if you have a potential sleep disorder, there's a merrygoround of medications that one may have to use to not acclimate to one or the other.
>
>
> But please don't mix alcohol with any significant quantity of them at bedtime.... its not a teetotaler's comment, its just well, I think common sense.
>yes- wine at dinner and sonata at night are to be enjoyed on separate occasions.
>
> Anyhow that's just my 2c, as everything, everyone will vary.
>
> -- tidings
>
> Jaythanks so much for your thoughts. Have a good night's sleep
poster:llurpsienoodle
thread:841684
URL: http://www.dr-bob.org/babble/20080727/msgs/842883.html