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Re: 2 days' worth of experimentation » llurpsienoodle

Posted by yxibow on July 29, 2008, at 2:08:54

In reply to 2 days' worth of experimentation, posted by llurpsienoodle on July 25, 2008, at 6:49:03

> Day 1) glass of wine at 7pm & sonata at 10:30 pm
> woke up at 5:00 am, stayed in bed until 5:30 am. Felt in a daze all day long. Kind of tired, but caffeine stimulated.

Okay -- here's where stacking sleep agents is a BAD thing. The half life of alcohol, for a female, I believe you are, but I could be mistaken, would still be in you when you took the Sonata. Not a good thing.

Sonata is fairly weak though as a sleep agent for most people.


> Day2) klonopin at 4pm & zolpidem at 10:30 pm. Woke up at 5, fell back asleep. woke up at 6, fell back asleep, got up at 7am. I feel groggy, but hopefully a cup of coffee can pull me back into the realm of the living undead.


Here we have an example of why Ambien won't work if you're taking Klonopin regularly. The pseudobenzodiazepine agents are fairly useless if you are already taking a benzodiazepine as they eventually all act on the sleep receptor of GABAa.


And yes, things have to be tried more than one time. But I can't emphasize enough that stacking sleep agents can get one into real trouble -- the desire to sleep leading to oh, well, I'll take a benadryl with some Ambien and.... yes, respiratory depression, coma, etc.


Of all the agents though, I guess I would either go for the Ambien or the Sonata. Habituation occurs much faster with any benzodiazepine.


It's not an "easy question". Sleep regulation is a hard thing, trust me, I have been through multiple agents. But then again -- everyone is different. I'm just saying if you have a potential sleep disorder, there's a merrygoround of medications that one may have to use to not acclimate to one or the other.


But please don't mix alcohol with any significant quantity of them at bedtime.... its not a teetotaler's comment, its just well, I think common sense.


Anyhow that's just my 2c, as everything, everyone will vary.

-- tidings

Jay

 

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