Posted by psychobot5000 on April 29, 2007, at 21:16:34
In reply to Re: Noradrenergics for motivation, focus, anhedonia? » psychobot5000, posted by mattdds on April 29, 2007, at 14:51:37
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> I've tried this route - the noradrenergics - to improve my energy, focus, and interest in life. My experience, is that they push me into irritability and anxiety very quickly. So far, I'm left to choose between functional anhedonia and overstimulation. Overstimulation, with absolutely no renewed interest in life or motivation. Personally, I'll take anhedonia anyday.
>That sounds like my brief experience on T3 (which I understand is supposed to enhance noradrenergic effects of meds somehow), and in that case, I too found anhedonia preferable to being a ball of tightly wound irritable anxiety. Wellbutrin felt much the same way, though not as bad.
As for Ines's comments on Reboxetine:
"Hi there, I tried reboxetine to treat depression, exactly because my depression comes with lethargy, lack of concentration... It made me manically energetic for about 5 days- but in a very uncomfortable way...but my mind was very agitated...and couldn't focus on anything at all. I also couldn't sleep for being wired up...."I took Reboxetine for...perhaps only a week--stopped it because I also felt anxious and wired up in a bad way...it doesn't seem a very effective AD from the experiences I read here. I'm sure Reboxetine has helped people, but I think it might not be an accident that they couldn't muster enough evidence of AD effect for the FDA to approve it.
Selegiline and DLPA is something I've sometimes wondered about--seems likely worth trying, but perhaps likely to cause insomnia too. I sometimes wonder why so many energyless, apathetic depressives have trouble getting to sleep as well. In any case, perhaps that would be a viable option, with something added for sleep--thanks for suggesting it.
Link, sorry to hear that Strattera made you tachycardic. I'm a little surprised, as I'm normally sensitive to that, and it didn't for me. But its positive effects disappeared very quickly anyway. I noticed you mentioned the idea of using beta-blockers with a noradrenergic. Does that seem like it would be a good combination? Since beta-blockers have the reputation for causing depression, I'd always wondered if one could get away with using them to control antidepressant or stimulant-induced tachycardia, without losing the mood benefits. Amineptine and nortriptyline made my heart race, damn them.
Interesting oats should be mentioned...likely nothing, but at some points in my childhood I insisted on eating oatbread, in part because I thought it made me feel better. ...Seems silly...
Anyway,
Psychbot
poster:psychobot5000
thread:754423
URL: http://www.dr-bob.org/babble/20070426/msgs/754545.html