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Re: XR: What Dosage Passes Serotonin Impact? dreamboat_annie

Posted by SandyWeb on March 6, 2007, at 15:50:55

In reply to Re: XR: What Dosage Passes Serotonin Impact? SandyWeb, posted by dreamboat_annie on March 6, 2007, at 12:19:39

Hi there Dreamboat Annie. Nice to meet another Crazy Canuck!!

>I had read on Crazymeds that at about 225 (if I am remembering right), Effexor XR works on norephedrine.<

Yes, that's why I'm trying to get up to the higher doses as quickly as my body will tolerate it. I was not doing well at all on 75 mg....I was just so "not myself", and even though I tried to stay with it, it just was making me whacko. Serotonin is not my friend. Lol.

>And, at some point (300mg?), it also hits dopamine.<

Hmmmm....dopamine is not too friendly with me either. It tends to shoot my heart rate way up....tachycardia time! But I'm on an anti-anxiety plus a beta blocker, so maybe it'll keep me safe from that.


>If the Effexor XR doesn't work, have you considered one of the TCAs that works most specifically on norephedrine, rather than serotonin?<


I've intentionally stayed away from both TCAs and MAOIs. They are just too dangerous, in my opinion. One can cause irreversible physical side effects, and the other you have to be so extremely aware of all the foods you eat....and knowing me, I'd eat cheese or something without thinking! I just find them too scary.

> I hope you continue to have success with Effexor XR as you continue to raise the dose.<

Thank you, thank you. I'll probably stay on the 150 mg for another 2 days, and then I'll increase to 225 mg. That may turn out to be the perfect dose. If not, I have permission to go to 300 mg....but I'm hoping that I won't need to be lugging these huge prescription bottles home from the pharmacy all the time!! LOL.

Take care and God bless,




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