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Re: XR: What Dosage Passes Serotonin Impact? Hagbard

Posted by SandyWeb on March 3, 2007, at 23:40:11

In reply to Re: XR: What Dosage Passes Serotonin Impact? SandyWeb, posted by Hagbard on March 3, 2007, at 19:16:44

> For me, 225mg/day is best during most of the year<

Well, jeepers, I almost felt like crying when I read your message. I had only been on Effexor XR 75 mg for a little over a week, and I just *couldn't* continue.....even though I knew it was basically my last option. But the serotonin impact was just TOO much for me. I need to get past that point and start targeting the other neurotransmittors. Not only was my insomnia way over the top, but I was focusing on events that had happened in the past (playing them over and over in my mind, day and night, like I'm reliving each step....such as a airline crash that I assisted in the morgue with and the times I slit my wrist), I start imagining fake incidents (like a plane crashing in the ballfield by my apartment or a car wreck down the road from me....things that haven't happened, but walking through them step by step....and NOT being able to STOP), my startle reflex is back with a vengence, I tense when I hear someone walking down the outside hallway (couldn't tell you why), my tummy is scared.......and all this even when I'm still taking anti-anxiety and beta blockers. DANG! So I stopped taking the 75 mg, and my brain said, "Thank you!!".

But now.....I really know that I can't just leave it at that. I can feel the depression wanting to make an entrance again, and I've got to DO something. And you mentioned 225 mg. Oh, I just want to cry. And that is actually one of the doses that the doctor told me that he thought I would have a response at. *sigh*

So.....I took 75 mg again tonight. I'm going to take another 75 mg tomorrow morning. The following day, I'm going to take a whole 150 mg at one dose. I know that is ramping up fast, but I'll dump the whole darn bottle of clonazepam down my throat if it will keep me calm during this (just an exaggeration, but you know what I mean). I'll wait at least 4 days on the 150 mg to see if my brain starts being busy and talking and thinking....and if it still is reacting like serotonin, I'll up it to 225 mg. From there, I'll just hold on until I either throw the pills away or go see the doctor.

As for therapy, I'm waiting to hear from a counsellor who would come to my own home to conduct therapy. I have social anxiety and agoraphobia, so it's rather difficult for me to get out to any appointments. The pdoc at the hospital said that he would get this set up for me if he I'm waiting. But right now I've just got to grind my teeth, hope the insomnia doesn't put my anxiety through the roof, and hang on for good results.

Thanks for the input. I appreciate it.

God bless,




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