Posted by yxibow on February 26, 2007, at 18:26:02
In reply to Re: xanax and grapefruite juice......did i do some, posted by becksA on February 26, 2007, at 17:52:48
> In what way does grapefruit juice affect meds?
Grapefruit juice theoretically affects some medications at CYP 450 (liver cytochromes) 3A4. This has not been proven to be hugely significant unless you're an absolute fan of grapefruit juice, which if the tangy bitter stuff floats your boat...
What happens is that grapefruit juice theoretically inhibits at 3A4, thus Valium or Xanax which are substrates will be left in the system longer and made more potent. I'd think you would have to drink the carton to make any dent in things, but some people might be more sensitive, its hard to say. There are other more significant medications that inhibit at 3A4 than the property of grapefruit juice, such as Luvox.
poster:yxibow
thread:736448
URL: http://www.dr-bob.org/babble/20070224/msgs/736551.html