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Re: SSRI's and the heart » madeline

Posted by Quintal on December 31, 2006, at 21:22:24

In reply to Re: SSRI's and the heart » linkadge, posted by madeline on December 31, 2006, at 20:22:53

>We haven't seen changes in blood pressure, bleeding times or much along those lines in people on SSRI therapy

Well I've seen bleeding disorders mentioned as a characteristic side effect of SSRIs here in the British National Formulary:
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The selective serotonin re-uptake inhibitors (SSRIs) have fewer antimuscarinic side-effects than the older tricyclics and they are also less cardiotoxic in overdosage. Therefore, although no more effective, they are preferred where there is a significant risk of deliberate overdosing or where concomitant conditions preclude the use of other antidepressants. SSRIs are also preferred to tricyclic antidepressants for depression in patients with diabetes. The SSRIs do, however, have characteristic side-effects of their own; gastro-intestinal side-effects such as nausea and vomiting are common and bleeding disorders have been reported.
http://www.bnf.org/bnf/bnf/52/3294.htm
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Although rare, it seems that bleeding disorders are associated with SSRIs and are cause of enough concern for the both the British Medical Association and the Royal Pharmaceutical Society of Great Britain to list it in their advice to GPs in balancing the risks of different classes of antidepressants.

Q


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URL: http://www.dr-bob.org/babble/20061224/msgs/718047.html