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Re: SSRI's and the heart

Posted by linkadge on December 31, 2006, at 20:40:20

In reply to Re: SSRI's and the heart » linkadge, posted by madeline on December 31, 2006, at 20:22:53

But, we already know that SSRI's can increase serotonin to a significant extent in other paripherial tissue. Ie. SSRI's can increase GI problems significantly in some patients. They are not just centrally acting.

People who already posess the SS varient of the serotonin transporter might also be at more significant risk, as SS varient + SSRI would have even more diminished SERT function, making them more like the SERT knockout mice.

I don't know. It scares me. I would be frightened to take the drugs long term. Sometimes when things start to pop up its too late.

I mean we take the drugs because they cause hippocampal proliferation. Serotonin promotes proliferation in a variety of human tissues.
Would it be of suprise if they cause growth in the heart too, like fenfluramine induced structural abnormalities?

I know I am paranoid.

Linkadge



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URL: http://www.dr-bob.org/babble/20061224/msgs/718040.html