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Re: Riluzole - SLS

Posted by rovers95 on December 22, 2006, at 2:20:35

In reply to Re: Riluzole - SLS, posted by SLS on December 21, 2006, at 6:33:15

> > Did you use a benzo alongside it????? I say this as when i took klonopin with the memantine the other week i felt very depressed............perhaps a case of no glutamate and too much GABA causing CNS depression!
>
> That's a good thought. How does Klonopin affect you otherwise?
>
> When I took riluzole or memantine, I did not take a benzo along with them.
>
>
> - Scott


I was fine on it before the memantine, if anything it had a v.slight AD effect on me as i did not have the racing thoughts - but memantine for me is more effective than a benzo!!

On the GABA glutamate subject, seen as lamictal upregulates GABA and you would also get a similar effect from the riluzole (i.e. also through voltage sensitive sodium channel blockade!)....perhaps this could be a reason for your poor response???!

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