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Re: Nicotine and Depression Questionmark

Posted by SLS on October 6, 2006, at 8:33:13

In reply to Re: Nicotine and Depression Questionmark, posted by MrBrice on October 6, 2006, at 8:04:04

> Aren't you speaking contradictious here? The nicotine raises the dopamine and thus gives a feeling of calm- and contentness.

I think nicotine causes the RELEASE of dopamine via nicotinic ACh receptors located on dopaminergic neurons. It does not increase the amount of dopamine.


> Nardil also raises the dopamine levels,

Yes. It increases the amount of dopamine available for release by preventing its degradation.

The two drugs work very differently.


- Scott

 

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URL: http://www.dr-bob.org/babble/20061003/msgs/692345.html