Posted by linkadge on July 2, 2006, at 16:20:46
In reply to Re: RESERPINE, posted by SLS on July 2, 2006, at 14:26:21
SSRI's don't necessarily depleat dopamine. They put the breaks on dopamine release. Dopamine might actually acumulate, but just not get released. When you stopped the SSRI, there was less inhibition on the dopamine release and hence more dopamine release.
Taking reserpine would be different as it would actually depleat brain dopamine content. Sure the postsynaptic receptors might upregulate but with less acutal dopamine to be released, I'd doubt it would lead to any euphoria.Linkadge
poster:linkadge
thread:663324
URL: http://www.dr-bob.org/babble/20060701/msgs/663595.html