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Re: anti-inflammatories and depression

Posted by SLS on June 4, 2006, at 19:43:47

In reply to anti-inflammatories and depression, posted by deli on June 4, 2006, at 18:34:21

> I was just wondering if anyone has felt better after taking anti-inflammatory drug (Celebrex). About 5 days ago my dr. prescribed some Celebrex for my shoulder and a muscle relaxant. That night I slept for 12 hours and when I woke up I felt better than I have felt in a long time. I continued taking it for 3 days and then stopped since the pain had subsided. A day or two later, I began feeling down and exhausted again. The only thing that had changed was that I stopped the anti-inflammatory med. Could there possibly be a link between depression and inflammation of the body in general and anti-imflammatory medication can be of help? What does anyone think?

Some researchers have noted an association between elevated levels of markers for inflammation and depression. It has been reported that CoX-2 inhibitors can improve depression is some individuals.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15551192&query_hl=6&itool=pubmed_docsum

I once tried doxycycline as a treatment for depression. One of the rationales for trying doxycycline is that it acts as an anti-inflammatory in the brain.


- Scott

 

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