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Re: Secobarbitural Sodium! » yxibow

Posted by ed_uk on February 17, 2006, at 14:56:23

In reply to Re: Secobarbitural Sodium! » ed_uk, posted by yxibow on February 17, 2006, at 3:07:42

Hi

>Severe panick attacks can also be solved by a 1mg or more of Xanax, which is also fast acting and safer, but not as cheap.

No, because barbiturates would only be suitable for patients who didn't repond well to benzodiazepines.

>I was putting a bit of this humour in the UK-US barbiturate argument. I assure you, they're not used as much here.

This isn't a UK-US argument. The barbiturates are almost never prescribed in the UK. The vast majority of UK pdocs will never have prescribed a barbiturate. I don't understand why you are under the impression than barbiturates are used more frequently in the UK, I very much doubt it. Sedative (eg. benzo) use is strongly discouraged in the UK. The benzodiazepines are treated with disdain here.........most docs probably don't even know that the barbiturates are still available.

>Yes, they're all presugery prep agents with the exception of Halcion, here, or conscious sedation, which has been banned most places.

Midazolam can be taken orally as a sleep aid. It is used in this manner in some countries.

> I know that certain epileptic disorders are very hard to control.. and you've hit the point right square that barbiturates are just plain cheap

Price doesn't come into it RE barbiturates in the UK. Phenobarbital is never used as a first line treatment for epilepsy in the UK. I was referring to developing countries when I mentioned the price of pheno.

>But benzodiazepines here aren't all that much more expensive. Trust me, a **** load of Valium is $20.

Phenobarbital is not the same as the barbiturate hypnotics (eg. Seconal), the anticonvulsant dose is less than the sedative dose. Other barbiturates are only anticonvulsant at doses which produce substantial sedation. Pheno's anticonvulsant efficacy may not be related to potentiation of GABAergic neurotransmission. Pheno has always been considered to be effective in the long term treatment of epilepsy, the same cannot be said of benzodiazepines, which are most suitable for emergency treatment of prolonged seizures. In some patients, clonazepam can be effective in the long term treatment of epilepsy, but tolerance develops in many.

>Very small. A script for 0.5 Xanax is equally effective.

No, because Seconal would only be prescribed if Xanax didn't work!

>even if we disagree on the NHS use of barbs :)

I never once mentioned the NHS! Barbiturates are very rarely used by NHS doctors.

>........and if she had a barbiturate in her hands instead of Xanax..... oh, never mind.

I'm sorry to hear that J.

>Soma is a barb cousin

Carisoprodol and meprobamate are chemically unrelated to the barbiturates.

Regards

Ed


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