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Re: Studies on long term use of SSRI's

Posted by law663 on November 25, 2005, at 22:30:52

In reply to Re: Studies on long term use of SSRI's, posted by Jakeman on November 25, 2005, at 20:39:51

Yes, but for most psychiatric drugs that is the case. I think we must remember that before the SSRI's came out we only had the typicals which were "effective" but only with HUGE side-effects which prevented most from having any semblence of a routine life. So, Prozac et al was a "life saver" but not perfect. What troubles me is that we have no idea if long term use of SSRI's is associated with alterations in brain morphology. Epidem people will say that there is no assocaition with SSRI's and cancer, heart disease, etc -- but that speaks nothing to things like pituitary disease, diabetes, or subtle disease.

> What has always been curious to me is the wild variations of efficacy that people report.
> Recently I was perusing the website
> askapatient.com
>
> http://www.askapatient.com/classreport.asp?class=ANTIDEPRESSANTS
>
> Prozac for example.. 224 people rated their experience. Several commented that it had saved their lives and had used it for years. Others said that the drug was worthless and/or dangerous. About as many people rated it 5 as rated it 1. The reviews are similarly mixed on other AD's.
>
> Maybe SSRI's are efficacious, but only for about a third of us.
>
> warm regards ~Jake


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poster:law663 thread:582087
URL: http://www.dr-bob.org/babble/20051119/msgs/582248.html