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Re: Studies on long term use of SSRI's

Posted by law663 on November 25, 2005, at 15:25:26

In reply to Re: Studies on long term use of SSRI's, posted by Chairman_MAO on November 25, 2005, at 12:45:28

That's interesting becasue I take 5G of androgel for a pituitary adenoma and while it as helped sexual funtioning somewhat (even with cialis) it's main effect has been improvment in mood. I take Cymbalta 30 mgs (once a day even days, bid odd days -- i find i don't need the full 60 mgs all the time). Additionally, I take 18 mgs of Concerta and noticed slight improvement in sexual functioning (it has some D2 agonist properties) but overall I still struugle with the full spectrum of sexual progams assocaited with SSRI's (but need the anti-anxiety effects of them).

> Taking a D2 agonist (think: pituitary) initially completely reversed my sexual dysfunction from buprenorphine+phenelzine. The effect went away, and it has never worked again, even at doses used by end-stage Parkinson's patients. I always like to mention that even at 8mg/day cabergoline had no detectable side effects in me.
>
> Taking testosterone propionate ~250mg/wk has eliminated any trace of drug-induced sexual dysfunction. This suggests that buprenorphine+phenelzine together many have a testosterone-lowering effect and/or some other deletrious hormonal effect. One study in buprenorphine maintained healthy, young male heroin addicts showed no lowering of T at 16mg/day, but in combination with phenelzine this may not be the case ...
>
>
> Given that many people on buprenorphine also take serotonergic psych meds, this warrants further investigation.


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poster:law663 thread:582087
URL: http://www.dr-bob.org/babble/20051119/msgs/582132.html