Posted by zeugma on November 1, 2005, at 21:49:27
In reply to Re: DPSP database clomipramine dopamine affinity, posted by linkadge on November 1, 2005, at 21:28:09
> >anticholinergic effects can impair memory, but I >seriously, seriously doubt that memory >impairment is the mechanism by which they may >contribute to alleviation of depressive states.
>
> THe TCA's are arguably more effective for certain depressive states than newer drugs, even say, effexor, which shares the TCA's dual uptake inhibiting properties. The main difference are the anticholinergic side effects. Anticholinergics are oftentimes euphoriants. I personally find anticholinergics very mood brightening. I found cogentin was an antidepressant.
>
> I personally do not doubt that impairment of certain aspects of memory can have antidepressant effects, so as to agree with Breggin's theory of "Brain Disabling Treatments", essentially where many "theraputic responses" in psychiatry correspond directly to impairment of some aspect of neurological functioning. What do ECT and TCA's have in common besides their higher efficacy in depression? Memory impairment, among other dirty consequences.>>why then is not Klonopin not an antidepressant? It causes cognitive impairments yet depresses people.
what about many AED's? people often complain that they impair memory but are not antidepressants.
Neurontin has been called "Morontin" by many posters and yet it has not been hailed as an antidepressant.
what was that notorious drug that was implicated in date rapes? Rohypnol? Shouldn't that by Breggin's logic be the ultimate antidepressant?
what I was trying to say in my previous post to you, but did not express clearly enough, no doubt beause i am on therapeutic doses of two 'dumb drugs' (clonazepam and nortriptyline) is that anticholinergic effects are antidepressant but that the effect is independent of cognitive disabling, because benzos cause arguably even greater cognitive impairment than TCA's and yet are not antidepressants.
-z
>
> Linkadge
>
>
>
>
>
poster:zeugma
thread:573553
URL: http://www.dr-bob.org/babble/20051031/msgs/574345.html