Posted by med_empowered on October 30, 2005, at 22:37:03
In reply to Re: DPSP database clomipramine dopamine affinity, posted by zeugma on October 30, 2005, at 22:28:01
hey! I think I've read that extended, high-dose clomimpramine use can sometimes lead to some form of TD...I guess this would be kind of like the cases of TD that pop up now and then with Effexor, and more commonly with amoxapine. Surmontil also has an odd, neuroleptic-ish effect; chemically, its a lot like loxapine...apparently, the D2 antagonism is really, really mild, so you don't see EPS, and I don't think there have been any problems with TD. The good news is that it can kind of function as a mood-stabilizer and antidepressant at usual doses, which makes it ideal for people with bipolar or more complicated cases of unipolar depression. I think I read a study where it was used for schizophrenia, but I dont think the results were all that promising.
poster:med_empowered
thread:573553
URL: http://www.dr-bob.org/babble/20051024/msgs/573627.html