Posted by SLS on August 20, 2005, at 7:45:17
In reply to Re: Remeron blocks SSRI side effects, posted by linkadge on August 20, 2005, at 0:28:12
> I'd try it, but I really just don't care anymore.
I hope this is just a passing phase, Linkadge. I have been through it before. To be honest, I have grown weary of investigating psych stuff and don't much care about detail anymore. I just want to know enough to put me on the right track or in front of the right doctor. Just give me the right drugs and let me begin living a life enriched with things other than knowledge of biological psychiatry. I'd be very happy not to know anything about the differential roles that the various 5-HT receptors play in favor of watching Jethro Tull in concert.
That being said, have you tried any of the neuroleptics that act as agonists at postsynaptic 5-HT1a receptors like ziprasidone or aripiprazole? Do you think gepirone might produce a therapeutic action as a partial agonist at these sites, or will it be as impotent as buspirone as an antidepressant? I wish flexinoxan were around. It is more potent than gepirone and lacks the NE alpha-2 receptor antagonist metabolite.
* Give yourself permission to be sick and tired of anything, but try to isolate which things are causing you feelings of helplessness or mental fatigue and put them away for awhile. You might find that you will find a renewal of energy and a more positive outlook. This might mean avoiding PB and psychiatric research for awhile. In the meantime, you will be able to deal with your true immediate priorities and perhaps gain a better insight into what things are acting as obstacles to your happiness.