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Re: Bzs questions Bromazepamto Darkhorse and everybody

Posted by darkhorse on May 23, 2005, at 9:22:37

In reply to Bzs questions Bromazepamto Darkhorse and everybody, posted by sdb on May 22, 2005, at 11:18:31

> Hi sdb,
>
> I have pretty good stabilizing effects with prazepam. It works more subtle and as you said 11 pm once daily intake. It's somehow activating but also makes you a bit tired. I think its an underestimated long-acting bz with interesting pharmacokinetics. I have taken it for eight days and stopped it immediately after testing without any problems.

I can not agree more about all your statement!

>
> You prefer Bromazepam.
>
> Is it possible to thake Bromazepam possibly once a day, what is your experience?

Yes,bromazepam is more of a longer acting BZ. It lasts 19+ hours for a 3mg.I've tried 6mg once a day in the morning and it lasted until next day.No feelings of any withdrawal at all.

You see, the higher the dose, the longer it stays in the body.But, like all other long acting BZ some people prefer to take them in divided doses twice or 3 times a day.

Personally, I prefer bromazepam because it is the least sedating (except Clobazam which did not fit my body chemistry),and that once you take before bedtime for a few days, you get a total tolerance of its very mild sedation,and then can be taken in the morninig.

If you do not suffer from chronic insomnia, to me bromazepam is the best daytime anti-anxiety medication (tiny cognitive problems,no sedation and drug accumilation(tiredness) (e.g.diazepam,clorazepate,prazepam,ketazolam) activation, mood-elevating proporties,no depression(Clonazepam),least amnesia(e.g. Ativan/Temesta), no space-out feelings (Xanax),no severe withdrawal effect (comparable to diazepam and prazepam)

Maybe I'm biased a bit....but I do not know... after trying those extremley famous BZ (e.g. Clonazepam,alprazolam,diazepam..etc)I reached a conclusion that famous does not mean better!!!
same as AD's.

>
> You once rated ketazolam as very sedating, is it true? Are there some other long-acting bz's I am possibly not aware?

I did not try it for long and maybe the fluoxetine I was taking at the time intensfied the effect.Also I took 30 mg a day which is not a very low BZ.It was not a bad one,but did not give it a long trial and can not remember why.

In my limited knowledge I will try to list you the longet to the shortest acting BZ which I've tried , so here goes nothing !!:


1.Prazepam,Diazepam,Ketazolam,Clorazepate and Chlordiazepoxide are the longest acting.(50-200hours)

2.- Bromazepam,Clonazepam,Clobazam,Flunitrazepam and Nitrazepam are also long acting - medium acting (20-40hours).

3- Delorazepam,Cloxazolam,Lormetazepam and Tetrazepam are medium acting (13-15 hours)

Short acting :

4- Lorazepam (12 hous)
5- Cinloazepam (9 hours)
6- Oxazepam and Alprazolam (6-8 hours)
7- Tofisopam,Bentazepam and Brotizolam (5 hours)
8- Zopiclone ( 4hours)
9- Triazolam and Zolpidem (3 hours).

* Hours are approximate,and all this info is based mainly on my trials.....
>
> Thanks for sharing experience.

THANK YOU for your kindness...
>
> Regards
>
Darkhorse.


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