Posted by sdb on May 13, 2005, at 15:57:40
In reply to Re: PRAZEPAM to darkhorse and everybody, posted by darkhorse on May 12, 2005, at 4:48:02
Dear darkhorse,
Thank you for sharing your knowledge. I would like to know more from your great experience in benzodiazepines.
I have some more questions relating to prazepam:
-On which day after beginning the treatment did you remark the highest "anti-anxiety" effect, how much was dosage and when intake (divided/morning/evening)?
-Could you compare diazepam to prazepam relating to diminish anxiety?
-How much (mg) diazepam = prazepam (mg) to diminish anxiety?
-Which drug diazepam/prazepam needed longer time to reach anti-anxiety effect?
-To which drug did you change? Why have you stopped your prazepam treatment?
My experiences:
After day seven of prazepam (20-40mg) I have almost no sedation, no muscle weakness, no cognitive problems, minor activating effects, slight subtle anti-anxiety effects.
After day seven prazepam seems for me to be a interesting alternative to combat longterm minor anxiety/depression symptoms.
The properties are totally different to clonazepam:
More muscle weakness, more antianxiety effect when plasma max but more anxiety than normal after elimination (no effective metabolites). More lethargic feeling. More sedation (therefore perhaps more "anti-anxiety" I dont know). Clearer defined time point of maximal "anti-anxiety" effect (3-4h) after one dosage intake (because of absorption and active clonazapem itself). More concentration problems. More balancing problems, it seems to have effect on vestibulocerebellum like ethanol. I have only used clonazepam in single intakes (4mg) and (2mg) during seven days.
Interestingly after longterm clonazepam intake according to some (duke panic studies) studies dosages can be reduced, but it dont seems to be related to steady-state plasma levels. Perhaps the same could be possible with prazepam. I dont know.
poster:sdb
thread:493236
URL: http://www.dr-bob.org/babble/20050510/msgs/497416.html