Posted by darkhorse on May 24, 2005, at 4:32:09
In reply to prazepam (centrax) one more please to DARKHORSE, posted by sdb on May 23, 2005, at 20:06:53
> Hi Sdb
> How would you rate bz's in cognitive impairment e.g. memorizing things, or attention?-Especially prazepam and bromazepam compared to others e.g. diazepam?This is a difficult question.
IMO, I think the relation between sedation and cognitive impairment is very weak.e.g I rate Lorazepam as not so sedating i.e. I have good concentration and can function very well.However, when I stop it, I'm not able to recall some things in details.
On the other hand a more sedating compound such as Clonazepam, when I took it I could not concentrate or do any work, felt blue and very tired, but when I stopped and all those nasty effects vanished, it seemed I was able to remember events (marginally) more than lorazepam.
Another better example is Clobazam (Frisum) :
Although it is the only BZ that is totally devoid of any sedation.when I took it, I "felt" like I'm functioning well and no tiredness at all (but due to its anxiety/aggression/unease effect on me I stopped).
However, when I stopped, I could not rcall very much how nasty I was!So, going back to your question:
1- in terms of "memorizing aspects" I think that all BZ tend to have this amnestic effects regardless of their sedation, but I rate Lorazepam,Cloxazolam Zolpidem and Lormetazepam as the strongest,and Chlordiazepoxide,Bentazepam,Bromazepam and Prazepam as the least amnestic.
2- In terms of " attention" I think that sedation here plays the major part : the more sedating, the more difficult to concentrate and do things.
Just a humble opinion!!
>
> Kind regards
>
>Darkhorse
>
poster:darkhorse
thread:493236
URL: http://www.dr-bob.org/babble/20050521/msgs/502142.html