Posted by ed_uk on January 27, 2005, at 13:08:18
In reply to Re: Desipramine and ADD » ed_uk, posted by zeugma on January 27, 2005, at 12:44:44
Hi Z!
>The antihistamine effect of NOR is also good for 'sleep hygiene' (i.e. it makes sure I get to sleep on time, and this is crucial for me). Not to mention, it helps my allergies.
The antihistamine effect might worsen your daytime drowsiness though. Also, it is possible that the 5-HT2 antagonism from nortriptyline is worsening your daytime drowsiness. You may prefer desipramine!
If you took desipramine instead of nortriptyline you could always take a short-acting sedative antihistamine to help you sleep. You could treat your allergies with a non-sedating antihistamine. Although desipramine is generally only modestly effective for most forms of anxiety, it is sometimes very effective in blocking panic attacks. If you find nortriptyline to be anxiolytic it is quite possible that you might also benefit from desipramine.
RE amphetamines.
To be honest, there doesn't appear to be any definate consensus on whether methylphenidate is more or less likely than the amphetamines to cause cardiovascular side effects.
Adderall causes more cardiovascular side effects than Dexedrine so it would not be a good choice for you. If you took Dexedrine immediate release you could adjust your regimen so that your plasma concentration of dextroamphetamine was low at meal times- this may reduce the risk of weight loss. A beta blocker may be useful for cardiovascular side effects. What cardiovascular side effects did you experience with methylphenidate?
Ed.
poster:ed_uk
thread:446337
URL: http://www.dr-bob.org/babble/20050124/msgs/448676.html