Posted by Nohope on September 9, 2004, at 3:57:06
In reply to Re: what is Milnacipran?, posted by SLS on September 7, 2004, at 13:09:05
> Milnacipran is a French SNRI drug that has been around for quite a few years. I have never spoken to anyone who has worked with it, so I don't have an impression as to its efficacy or side effect profile.
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> - ScottI was on milnacipran for a few months earlier this year (dose varied: 75-150mg).
I found it extremely tolerable. Some annoying start up side effects such as insomnia and nausea, but these passed. Very few side effects remained after 2-3 weeks.
For me, it was more potent as an antidepressant than the SSRIs, but that's not really surprising since I don't respond well to SSRIs. Unfortunately, it had no effect on my very strong fatigue (atypical depression guy here...) and I could only work and sleep, so I had to ditch it. It was moderately effective for my panic.
There is a rather large study suggesting that milnacipran was similar in efficacy to imipramine and superior to fluvoxamine. Maybe it's true, but I've never taken imipramine, so I can't say for sure (anyway, I am only a sample size of n=1).
Overall, it was definitely better than nothing and very tolerable, but not good enough for me.
(BTW check out its structure: hauntingly similar to Parnate)
Nohope
poster:Nohope
thread:380308
URL: http://www.dr-bob.org/babble/20040904/msgs/388552.html