Posted by SLS on September 7, 2004, at 18:51:41
In reply to Re: Milnacipran » SLS, posted by nmk on September 7, 2004, at 17:38:50
Hi again.
> > I would have thought Yasmin to be the better choice for PMDD
> He did try me on Yasmin but the progestin in the pill sent me spiraling downward into a serious depression.
I knew that was a possibility, but I thought it was less so with drospirenone. Darn.
> Please convince me why you would try the nortrip. and the nardil.
I think I would ask the doctor why he chose clomipramine over the other TCAs. His reasons might be compelling. Nortriptyline and desipramine do have milder side effect profiles. Clomipramine is sort of a cross between imipramine (from which it is derived) and an SSRI, and has the side effects of both. I'm sure your doctor wants to give you the best possible chance of responding to treatment. The question comes down to whether or not you would prefer to try first the drug with the fewer side effects before moving on to one with increased side effects, but with perhaps a higher probability of working.
Parnate is generally more forgiving than Nardil regarding side effects. It produces less problems with hypotension and anorgasmia, and is easier on the liver. Nardil can also produce edema. Although both MAOIs are capable of treating both depression and anxiety, Nardil seems to be more effective for the latter. Parnate can sometime exacerbate anxiety and agitation because of its stimulant properties. Ask your doctor what he thinks about this.
> I am trying to research as much as I can but I wind up even more confused.
Instead of using this information to make a decision in the absence of your doctor, perhaps it would be better to use it to discuss with him his reasons for choosing certain drugs versus the advantages and disadvantages of the others you have researched. You might end up agreeing with his choices. For instance, his reason for choosing clomipramine might be because he feels that you were partially responsive to SSRIs. Hopefully, he will be able to clear up any confusion.
- Scott
poster:SLS
thread:380308
URL: http://www.dr-bob.org/babble/20040904/msgs/387801.html