Posted by elleff on August 23, 2004, at 0:54:56
In reply to Re: The Truth about Stimulant Tolerance, posted by elleff on August 23, 2004, at 0:50:27
> Dear Philidor
> This may be of no use nor benefit, but I post this link because I happened to come across this old paper recently:
> "Inhibition of Amphetamine Tolerance and Metabolism by Propranolol" - Shoeman DW, Sirtori CR, & Ararnoff DL, Journal of Pharmacology and Experimental Therapeutics (1974) v191 (1):68 - 71.
> This reports studies on the pharmacokinetics and anorectic effect of amphetamine on laboratory rats, which showed, from my amatuer reading, an inhibition of amphetamine breakdown rather than any alteration in pharmacodynamics.
> I haven't seen nor heard any references to similar effects on humans on this board or elsewhere however.
PS sorry, forgot to include the link (but it's not much use because no abstract available):