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Heinrich Dreser and facination with acetylation. djmmm

Posted by MB on July 8, 2003, at 10:59:42

In reply to Re: Ah, come on!, posted by djmmm on July 8, 2003, at 8:17:06

I guess Heinrich Dreser loved to stick acetyl groups on molecules. He came up with aspirin by adding an acetyl group to salicylic acid (yielding a more tolorable side effect profile) and he came up with heroin by acetylating morphine. It's kind of funny when you think about it...two major sucesses (well, maybe heroin was a *little* bit of a problem child, but it *did* work) by simply acetylating already useful medications.





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