Posted by viridis on February 26, 2003, at 14:27:37
In reply to Re: Don't split Strattera caps according to Lilly, posted by not exactly on February 26, 2003, at 14:10:19
I've mentioned this here before, but will repeat my experience with Wellbutrin SR. The literature says don't divide them, and people seem to think that this is because they have a slow-release coating. But when I called GSK and spoke with one of the people who actually developed the slow-release form, he said that splitting the pills was fine, and they'd even tested this quite extensively. The slow release is controlled by the wax matrix inside, which dissolves at the same rate whether split or not. When I asked why they discourage people from splitting them, he said it's just because it's hard to get accurate dosing (the pills aren't scored so don't split exactly evenly). Also, if they sit around split for days, they take up moisture from the air. But the product info makes it sound like splitting the pills will cause dire consequences. It certainly didn't for me.
I have no idea whether this applies to Strattera (which I realize is a capsule), but it's a case in point with many potential parallels.
poster:viridis
thread:133458
URL: http://www.dr-bob.org/babble/20030224/msgs/204046.html