Psycho-Babble Medication | about biological treatments | Framed
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Posted by wingedcat on February 16, 2003, at 18:57:54

In reply to ANYONE ON SELEGELINE? QUESTIONS..., posted by Craig Allen on February 14, 2003, at 19:16:05

> i am a treatment resistant, atypical depression guy. most of the time i am sleepy and bored. i am on adderall (20mg, 3x per day) because it keeps me awake which enables me to stay employed. at first, the adderall was mood elevating. now it makes me feel flat and dull. i've read on this board that people have had a good response to selegeline (eldepryl). i have a few questions:
> 1) is there a rebound effect with selegeline, as there is with stimulants?
> 2) how long before it starts to work?
> 3) what drugs can, or can't, be combined with selegeline?
> 4) taken orally, what dosages are people finding to be effective? how long does it take to build to that dose?
> 5) before starting on selegeline, do you have to be off all meds for 2 weeks, as with other MAOI's?
> anything else about your selegeline experiences would be greatly appreciated. thanks for your help in advance.

I responded to another post of yours about selegiline here:

but here are answers to these particular ?s:
1) I've tried Adderall before too and I didn't like the rebound. I haven't noticed any rebound with selegiline.
2) I noticed it the first day. I had been suicidal because of the anhedonia/numbness. The first day I started selegiline I was able to cry and let loose a lot of feelings I had been keeping inside. Crying doesn't *sound* good but it was theraputic for me because I hadn't been able to cry for a long time.
3) You can't take opiates in any form, especially Demerol, you could die. I think it's this way with all MAOIs. As for stimulants, you should take a lower dose. I read someone on here combining a low dose of Dexedrine with Selegiline and having good results.
4) I was fine with 5mg a day, but I am small. 10mg a day (divided into two doses) is what I think is normally used in depression.
5) I think selegiline reacts less with most drugs than other MAOIs. If all you are taking right now is Adderall, that gets out of your system very fast. I think that the 2 week rule refers more to SSRIs.




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