Posted by JohnL on February 15, 2003, at 7:18:14
In reply to ANYONE ON SELEGELINE? QUESTIONS..., posted by Craig Allen on February 14, 2003, at 19:16:05
I have tried selegeline, though only in the 5mg to 10mg range.
Most psychiatric drugs actually make me feel worse instead of better. But selegeline was one of the few good ones. Oddly though, it made me impotent. It is supposed to be pro-sex, but it wasn't for me.
I actually felt good effects from selegiline the very first day. It was sort of like stimulant. But very quickly tolerance builds up and that stimulant feeling goes away.
I did not experience a rebound effect.
For me it started to work the first day, but I've heard others say it can take a few weeks.
When the selegeline dosage is 10mg or lower, there isn't much problem combining it with other meds. But above 10mg it starts to act like a full fledged MAOI, in which combinations demand a more cautious "low and slow" approach.
Some people find benefits in the 5mg to 10mg range. Others have had to go up to 40mg. You'll just have to experiment.
As long as you start out in the 5mg range, you won't need to do a washout.
> i am a treatment resistant, atypical depression guy. most of the time i am sleepy and bored. i am on adderall (20mg, 3x per day) because it keeps me awake which enables me to stay employed. at first, the adderall was mood elevating. now it makes me feel flat and dull. i've read on this board that people have had a good response to selegeline (eldepryl). i have a few questions:
> 1) is there a rebound effect with selegeline, as there is with stimulants?
> 2) how long before it starts to work?
> 3) what drugs can, or can't, be combined with selegeline?
> 4) taken orally, what dosages are people finding to be effective? how long does it take to build to that dose?
> 5) before starting on selegeline, do you have to be off all meds for 2 weeks, as with other MAOI's?
> anything else about your selegeline experiences would be greatly appreciated. thanks for your help in advance.