Posted by LAURA777 on February 14, 2003, at 7:14:19
In reply to another version (for Laura), posted by not exactly on February 9, 2003, at 23:10:05
> "God grant me the SEROTONIN to accept the things I cannot change,
> the NOREPINEPHRINE to change the things I can,
> and the DOPAMINE to care which is which."
>Hey Bob , heres another version which i think more closely fits my situation ..
"God grant me the SEROTONIN to accept the things I cannot change,
the NOREPINEPHRINE to change the things I can,
and the ENDORPHINS to care which is which."
if you read about the HPA axis and the production of CRF ACTH and high levels of cortisol in the blood of depressed patients and substance abusers ( heroin when activiely taken lowers the NE and cortisol , that is why when someone withdrawals from heroin there is a backlash of high NE production ).. high levels of cortisol cause a dysfunction in the way opioid peptides are able to respond , it hinders them ..normal cortisol levels and when the negitive feedback loop is sucessful opioid peptides get released to conterbalance the stress anxiety reaction .. it is part of the checks and balances of our system .. dopamine is a neuromodulator of opiate peptides and opiate peptides are a neuromodulator of dopamine as well .. it depends what is happening in the system .. under stress that is not long acting, opiate peptides are released to counter balance the surge of norepinephrine in the flight of fight of stress .. but in chronic stress , for whatever reason , some people are very sensitve to stress , thier HPA axis goes into overdrive .. they believe that is why some people are more likely to become alcoholics and drug abusers .. we take substances to reach homostasis because of lack of opiate peptide production .. Sensitivity to Norepiniephrine or too much ??? i don't know ?? or your theory about dopamine converting to NE to fast ?? these could all be likely .. NE is the excititory neuro that acctivates the sympathetic nervous system , i have an overactive or sensitive (i do not know which ) sympathetic nervous sys.. i sweat under my arms way more the most people , fast metabolism , enormous energy hyper ,(except when i am bored and have to push this saps my energy late in afternoon), also tremendous ability to focus .. and theres the fact that i am sensitiive to all and evey stimulant .(even that little bit that they deliver with the novicaine in the dentist ) .There is more , but if you are not interested , i won't take up your time .. so let me know , thanks , laura
poster:LAURA777
thread:138954
URL: http://www.dr-bob.org/babble/20030214/msgs/200337.html