Posted by LAURA777 on February 7, 2003, at 19:11:35
In reply to Re: Mirapex/Selegiline/Parnate » jumpy, posted by not exactly on February 7, 2003, at 16:30:40
Hi Bob , it sounds like you have a fast metabolism too ,, are you also sensitive to ephedrine products in cold meds ?? i do not know if you read my post but the provigil sent me flying .. yuk , the doc gave me 200 mg. i took one at 10.00 am and was up to 3.00 am , and the day before i took one at 8.00 am and stayed up till 3.00 am . i felt miserable physically and emotionally , nervous energy .. needless to say i will not take anymore .. also i could not eat at all .
i read somewhere that tyrosine converts to dopa then dopa converts to dopamine ,then dopamine to norepinephrine then to epinephrine . i have also read that if you have a fast metabolisim that you have plenty norepinephrine .. if that is the case . where is my dopamine ???
when you go to the dentist does epinephrine bother you in the novicaine , do you get a reaction ..
i do hope that i can find a solution because i am miserable .
Bob what is responsible for motivation and interest , i get conflicting reports when i read , some say it is norepinephrine some say dopamine .
Also do you think the mesolimbic system is responsible for anhedonia ?? do you think a deficiency in opiods is responsible too ..??
What do people do ?? i can't bear to think i have to be like this till i die ..
bupenorphrine is something i would like to try . because of the positive feelings i had with percocet and vicodin ..
i think my energy level is fine , it is the boredom that sends me to sleep , and it is hard to wake in the mornings cause i know what is ahead of me . more boredom .. and the endless push .. and because i have to push i get tired.. this routine would sap anyones energy .
i see alot of links that link cocaine abuse to anhedonia . and i also see also of links about drug/alcohol abuse in general causing anhedonia , and they also say it is prexisting genetics .
i have also read that constant stress raises our level of norepinephrine fight or flight and if we get enough stress for too long are endorphins become no longer able to work .. hence blunted feelings like post tramatic stress disorder ..
do you think having constant high levels of norepinephrine all through the years of your life cause this also ??? please let me hear what you have to say on many of my questions , i do thank you for you time ,laura