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Re: Question for you - Xevious » BekkaH

Posted by Iago Camboa on July 26, 2002, at 5:00:38

In reply to Question for you - Xevious, posted by BekkaH on July 25, 2002, at 5:54:40

> Xevious,
> Are you sure that the CNS/PNS stimulation issue of the d and l isomers is only subjective and not scientifically proven? I've read about this in so many places, including some psychopharmacology texts, so I'm wondering whether it is just subjective.

Hi Bekka,

Of course it is you (and all the world with you) who is right about the ACTUAL (OBJECTIVE) differences between the properties of Dexedrine (= d-amphetamine, the 'good' enantiomer) and the l-amphetamine, as is the rule with 99.99% of substances that happen to appear in both l- & d- varieties: the rarer in nature is the two being equally active. And there is NO such thing as people (whose body) 'prefer' the -l variety and people who 'prefer' the -d (that would mean different genetic material (not less!!) and would be impossible for any two individuals of our species).
It is an absurdity, as impossible as one person whose body had one certain aminoacid of the d-variety instead of the actual one (of the l-variety); that person could not even eat terrestrial food as all life on earth is based on the exact same aminoacids (mainly of the l-variety) and our enzymes are encoded genetically and built that way that they are only able to deal with one and only one of the two (theoretical) possible enantiomers: just the one that happens to appear naturally in our planet. It is the nature of things, as sure as all electrons being negative and protons positive.
There is no need to 'prove' scientifically that d-amph is much more active and is more CNS oriented & l-amph is more PNS oriented: it is a simple fact of life, one compound happens to have the properties such & such and the other some other properties. In my opinion our friend Xevious is an intelligent guy but has yet to learn many things (as we all have) and get a little more 'common sense' before he can post 100% reliably to his own self-enjoyment and the benefit of all PB community.

Kind regards,
Iago


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poster:Iago Camboa thread:113464
URL: http://www.dr-bob.org/babble/20020725/msgs/113778.html