Posted by Fuscia on July 7, 2002, at 21:52:30
In reply to Re: Vitamin B's -TD exasperbation? , posted by Fuscia on July 7, 2002, at 12:44:08
Hello,
I wanted to add that the best B-vitamin complex brands are those sold in divided doses, so you only receive a small amount of each B vit at one time. Mega doses at one time are not good. Vitamin B complex, or a multi vit/min with a high amount of vitamin B's should not be taken late in the day as the B vitamins increase energy and thus can cause insomnia, as well as anxiety for certain individuals. I take a B-complex that contains a 50 mg ratio for 4 capsules. I only take one, two tops, a day and not every day. Mainly because I forget to take them, but also I don't want to over do it. A much safer form of B vitamins is found in Nutritional Yeast and Brewer's Yeast as these products contain much small amounts than what you would find in many multiple vit/mins, as well as B-complex supplements.
From what I found out by searching the internet, and there is much that is not known about the cause of tics, is that tardive dyskenisia can be a result of dopamine oversensitivity. Vitamin B6 is a cofactor in dopamine production. Dopamine and its agonists play an important role in cardiovascular, renal, hormonal, and central nervous system regulation through stimulation of alpha and beta adrenergic and dopaminergic receptors. Stimulation of adrenergic receptors as a result of increase in dopamine can cause tics as well. There appears to be a reciprocal seesaw relationship between acetylcholine and dopamine and their respective nerve cell systems, so if you increase dopamine, it can result in a decrease in acetylcholine.
The tardive movement disorder would seem to occur when the increased sensitivity "overshoots" and causes increased muscle activity. Minute amounts of dopamine, which in the past were not enough to stimulate the receptor mechanism, now stimulate the sensitive receptors and cause movement in the muscles. If this is the case, you would want to watch your intake of vitamin B 6 if you have tics. Other symptoms of excessive dopamine include bruxism (teeth grinding), constipation, dry mouth, sexual dysfunction, and urinary retention. Highly excessive amounts can cause confusion, delirium, and hallucinations.
Something else to consider is the brand of vitamin or mineral you are taking. If one brand is giving you problems, you might consider switching to another brand to see if any unwanted effects disappear. My husband saw an article on the news of some independent consumer lab testing batches of different vitamin and other supplement brands and found that some contained trace amounts of steroids.
I'm all for taking supplemental vitamins and minerals, but do so cautiously and take below the suggested dose. I also agree with the post about Milk Thistle extract. It does wonders for the liver as tests have shown. It is best taken with lecithin. Take lecithin just before a meal and the milk thistle supplement after the meal. Milk Thistle protects the liver from toxins and pollutants by preventing free radical damage. It also protects the kidneys. CoEnzyme Q-10 is also something I take regularly for it is a powerful antioxidant (also called ubiquinone). According to Prescription for Nutritional Healing by Phyllis Balch, CNC, and James Balch, M.D. "This substance plays a critical role in the production of energy in every cell of the body. It aids circulation, stimulates the immune system, increases tissue oxygenation, and has vital anti-aging effects. Deficiencies of coenzyme Q 10 have been linked to periodontal disease, diabetes, and muscular dystrophy. Research has revealed that supplemental coenzyme Q 10 has the ability to counter histamine, and therefore is beneficial for people with allergies, asthma, or respiratory disese. It is used by many health care professionals to treat anomalies of mental function such as those associated with schizophrenia and Alzheimer's disease. It is beneficial in fighting obesity, candidiasis, multiple sclerosis, and diabetes."
Take care, Fuscia
poster:Fuscia
thread:111449
URL: http://www.dr-bob.org/babble/20020628/msgs/111702.html