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Re: Question for Dr. Goldberg Cecilia

Posted by Psydoc on April 21, 2002, at 7:54:16

In reply to Question for Dr. Goldberg, posted by Cecilia on April 21, 2002, at 0:23:45

I have treated about a dozen people with "treatment-resistant" unipolar major depression with Lamictal. Despite their being individuals who had not done well with multiple previous treatments, about half showed meaningful improvement with Lamictal. Doses of about 400 mg/day continued for 6 to 8 weeks were typical.

There is little in print about the use of Lamictal to treat patients with unipolar depression. A letter by T.M. Maltese on the topic can be found in the November 1999 issue of the American Journal of Psychiatry.

Best regards . . .

Ivan Goldberg
psydoc@psycom.net
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

> Of the patients you have treated with Lamictal, how many have had unipolar depression and what percent of these improved? I started Lamictal on Jan. 1, have been increasing the dose very slowly-upto 150 mg now (plus trazodone, celexa and clonazepam) no benefit yet-just wondering how many unipolars really do get any benefit from it. Thanks. Cecilia


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