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Re: NMDA antagonist neurotoxicity » JohnX2

Posted by christophrejmc on March 24, 2002, at 12:08:18

In reply to Re: Frontal lobe syndrome » BarbaraCat, posted by JohnX2 on March 24, 2002, at 5:45:56

What is your take on NMDA antagonist neurotoxicity ("Olney's Lesions")? I could only find a few articles on MedLine, but I haven't looked too hard. Have you seen any reports of this with NMDA antagonist use? I believe it has been shown to happen with memantine/dextromethorphan/etc. As far as I know, it's only theoretically possible in humans, but it is kind of scary.

-chris


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URL: http://www.dr-bob.org/babble/20020322/msgs/99862.html