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Re: NMDA theory of schizophrenia, etc. » JohnX2

Posted by christophrejmc on March 25, 2002, at 23:34:30

In reply to Re: NMDA antagonist neurotoxicity » christophrejmc, posted by JohnX2 on March 24, 2002, at 21:55:38

> It seems a lot of people aren't in harmony on this pcp based theory of schizophrenia.

Fer sure. It is interesting that the NMDA-antagonists induce both positive and negative symtpoms (or do the other psychotomimetic drugs do this as well?)... Perhaps this will lead to a novel treatment for the oft ignored negative/cognitive symptoms of schizophrenia.

There seems to be a dearth of information regarding neuroleptic-resistant schizophrenia. My psychiatrist (who spent a while practicing in one of our many long-gone (damn republicans!... sorry) psychiatric hospitals) told me that the hallucinations are often quite unresponsive to neuroleptic treatment.

> BTW, how is the Selegiline trial going?

Slowly. I'm at 30mg now and am getting some mild, but annoying cardiovascular side effects. It's effects on mood are strange... slight elevation but with no blunted affect (I'm a chronic apathetic partial responder).

Are you still thinking about adding Li to your current regime? SLS's posts have me interested in trying low-dose Li. I didn't have any side effects for the one(!) day I was on it before.

Cheers,
Chris


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URL: http://www.dr-bob.org/babble/20020322/msgs/100174.html