Posted by IsoM on February 10, 2002, at 14:10:14
In reply to MUST READ (deprenyl, klonopin, adderall, wellb..) , posted by Jason911 on February 8, 2002, at 4:01:05
Don't know if you saw my other answer to you but I've copied & pasted, in case you haven't. I really don't know if my information would work for you but since you asked...
I wouldn't try Deprenyl first off. Two of the studies are old (1978 & 1984) & while they're still applicable, there's so much more known about the brain's neurotransmitters now, at least compared to then & the interaction between them is much more complicated than imagined. The catecholamine based theory of depression seems right but I'm not sure our approach is always right.
I do agree that it's important to provide the necessary precursors in our diet for neurotransmitter synthesis which is why I foolow a GOOD, balanced diet & take extra supplementation. I can feel the difference, subtle but real nonetheless, when I take nutritional yeast flakes (high in B complex vitamins & many minerals) & from when I get lazy & let it slide.
Like you, I have serious problems with motivation, concentration, & focus. I also have mild enough narcolepsy & ADHD plus regular depression, worse in winter. When I was young, I 'self-medicated' too & of all the drugs taken, it was speed (meth) that was the most wonderful. So wonderful, it scared me as I wasn't ignorant of addiction, seeing it in others. It made me feel SO normal, but I was too scared to ever use it again.
When Dexedrine was prescribed for me many years later, it felt good too though not as powerful. But I hated the way I'd feel when the dose wore off - sleepy & blah again. And I noticed if I used it regularly, it started to lose effect. I nneded frequent 'holidays' from it. Ritalin felt even more up & down.
I read about the use of Provigil (modafinil) for narcolepsy in a science journal & in researching it found adrafinil & this forum where I lurked for a while. Adrafinil has been my god-send giving me a life again with enthusiasm. Rather than write it all out again, I hope you don't mind me providing a link to an old post. There's a number of us modafinil/adrafinil users here who really love the stuff. Rather than inhibiting or blocking re-uptake of transmitters, it seems to increase the brain's over-all metabolism. It's still not well understood (but neither are traditional ADs).
Here's my old posting link:
http://www.dr-bob.org/babble/20020116/msgs/90699.html (If you want to check out more posts on adrafinil/modafinil, I'm sure you know how to.)And here's an article on adrafinil (it's main metabolite is modafinil [Provigil]) from CNS Drug Reviews, 1999:
http://www.nevapress.com/cnsdr/full/5/3/193.pdf
poster:IsoM
thread:93294
URL: http://www.dr-bob.org/babble/20020208/msgs/93608.html