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Re: MAOIs and sleep problems » Elizabeth

Posted by Grouch on August 5, 2001, at 21:59:07

In reply to Re: MAOIs and sleep problems » Grouch, posted by Elizabeth on August 5, 2001, at 8:12:07


Hi Elizabeth. I'm glad you answered since you seem to be the resident MAOI guru around here.

> That was a problem for me with MAOIs too. Their widespread effects on aminergic systems seem to blow the whole circadian cycle to bits.

They sure do. See my previous post.

>I have a book somewhere that discusses their effects on sleep in depth, but I'd need to dig around to find it (I moved recently).

That would be great if you can find it. Even if you can just get the title & author I may be able to find it at my local medical library.

> Adding Ambien to the MAOI was somewhat helpful for me, and I didn't grow tolerant to it.
>
> One thing that's sometimes suggested is melatonin. I'm not too sanguine about adding that to MAOIs, though: when I tried a small amount, it kept me up all night (even with Ambien), I was sweating excessively, and my pupils were very dilated.

I tried melatonin once with Marplan. My former pdoc suggested it, though I'm pretty sure the potential risk didn't even occur to him at the time (he didn't warn me about it). Anyway, I didn't have any serious adverse effect, but I felt really hung over the following day, and I can't recall if I slept any better or not.


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