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Re: MAOIs and sleep problems » Grouch

Posted by Elizabeth on August 6, 2001, at 12:10:49

In reply to Re: MAOIs and sleep problems » SalArmy4me, posted by Grouch on August 5, 2001, at 21:30:29

> I've tried moclobemide and selegiline... they don't hold a candle to the non-reversible MAOIs IMO.

Selegiline is an irreversible MAO-B inhibitor that inhibits MAO-A at higher doses. It also has amphetamine metabolites

There is an irreversible MAO-A inhibitor, clorgyline, but as far as I'm aware it has never been used clinically.

> Never tried Sonata or Ambien so that might be worth a shot.

I think so.

BTW, the book I referred to in my previous post is _Clinical Advances in Monoamine Oxidase Inhibitor Therapies_, Kennedy ed. (1994).

-elizabeth


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