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Re: MAOIs and sleep problems » Grouch

Posted by shelliR on August 4, 2001, at 22:38:01

In reply to MAOIs and sleep problems, posted by Grouch on August 4, 2001, at 21:26:44

>
> MAOIs (Parnate & Marplan) are the only antidepressants that have been helpful for me. Unfortunately, I'm not able to tolerate them due to numerous side effects, especially sleep problems (insomnia, disrupted sleep cycle).
>
> I've tried benzos and trazodone, neither of which worked very well and had side effects of their own.
>
> I haven't been able to find much information on *how* MAOIs actually disrupt sleep. (Is this even known?) Are there other ways to combat this side effect?
>
> Appreciate any info...

Hi Grouch.
When I took nardil, I also had severe sleep problems. I started to take atarax (hydroxyzine) 150mg as well as 2mg of klonopin before bed and that did the trick for a 30-45 mg. dose of nardil. Over 45mg, nothing seemed to help with sleep. I had no trouble falling asleep but I wake up every three hours: Really wake up and it would take more benzos to finally fall asleep. You might try augmenting the MAOI and trying a smaller dose. My best combination was nardil and lamictal, but I gained a lot of weight on lamictal, so I choose to go off. By the way, that is not a common side effect of lamictal.

On Monday I am going to start parnate and am hoping not to have the same sleep problems as on the higher dose of nardil. Your post is not encouraging :-).

Shelli


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