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Re: Remeron - less sedation at higher dose? » Lupercal

Posted by Elizabeth on July 4, 2001, at 21:45:06

In reply to Re: Remeron - less sedation at higher dose?, posted by Lupercal on July 4, 2001, at 2:12:07

> Hi, Elizabeth

'ay.

> I should stress that I had _great_ success with the AD qualities of SSRI's - just that the screaming tinnitus was unbearable.

Hmm. What about Effexor? Clomipramine?

Any idea what the tinnitus is related to? Did you talk to a GP about it?

> Luvox in particular had a magic bullet effect, improving my mood substantially within 8 hours!

When I hear stories like this, I am always weirded out. That's not *supposed* to happen! (I guess that we don't all work the way we're "supposed" to, eh?)

> I read that one of the doc's who authored one of the orignal studies strongly recommended starting people at 30, but all the other literature suggests slow increase.

I dunno about the literature. I'm just saying what worked for me (my pdoc generally prefers to do it that way, starting at 30 that is). Also I've heard of a lot of people who started at lower doses and had bad problems. Some people still have side effects at the higher doses; if 30 isn't high enough, it might take 45 or 60 (which are more effective doses anyway). I noticed *no* side effects from Remeron at all.

> However, if starting at 30 would avoid the sedation - and if it's _nescessary_ to start at 30 to avoid the sedation, I would be willing to try. My main reason for wanting to start at a lower dose is ion case there is a tinnitus (or other unwelcome) side effect.

Remeron isn't an SSRI, and it has antagonist effects at some types of serotonin receptors -- in some cases, it reverses side effects of the SSRIs, such as sexual dysfunction and nausea. Tinnitus is not so common, but it might be that even if Remeron didn't work by itself, you could add an SSRI and the Remeron would prevent the tinnitus.

> I'm rambling, sorry.

I'm hardly in a position to hold that against you. :-)

-elizabeth


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