Posted by Lupercal on July 3, 2001, at 7:24:41
Hi.
I have tried 8 AD's thus far without success. SSRI's work great on my depression, but had to discontinue them all because of horrible (non-reversible) tinnitus side effect * I am about to start on Mirtazapine (Remeron).
Previously I have tried Mianserin, which I understand is a very close analog of Remeron. It made me totally bombed out; couldn't get out of bed. After two weeks I was more depressed than when I started. I'm expecting Remeron to have the same effect, however a lot of what I'm reading is that, in theory anyway, the sedation (and possibly weight gain) side effects are inclined to disappear at doses above 30mg per day. I read one comment by someone who said that at 30mg it acted like a sedative, but at 45mg like a stimulant!
Has anyone found this to be true? If so, how high a dose did you need to go to, to get away from the sedation effect? I seemed not to be adjusting to the sedation effect of mianserin, so I don't think time alone will do it. I'm due to go overseas in two weeks, so if possible I want to get up to a non-sedating dose as quickly as possible. (Naturally I will start on 15mg to make sure there aren't any nasty, weird side-effects, though)
Would also be interested in hearing from anyone who has taken both Remeron and Mianserin, to compare their experience of the two drugs - though such a person will probably be hard to find in the US.
Thanks
Loop
*this isn't strictly true: Celexa and Prozac gave me irreversible tinnitus, Luvox and Zoloft reversed, but I only took one or tablets of those before quitting.
poster:Lupercal
thread:68802
URL: http://www.dr-bob.org/babble/20010701/msgs/68802.html