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Re: 1 person's view.

Posted by Elizabeth on May 18, 2001, at 20:34:09

In reply to Re: 1 person's view. loosmrbls, posted by JahL on May 18, 2001, at 11:42:52

> We *know* that opioids are very habit-forming for most people

I don't think it's even most people -- only about 30% of people who try opioids find them pleasant.

> This board stands testament to the fact that not all people are alike in their responses to drugs.

*Oh yeah*. Most people assume that opioids are simply CNS depressants. In fact they have excitatory properties as well. For me, these are more pronounced: opioids are activating. The sedation is something that people generally adjust to; it isn't a problem in the long term.

The comparison to tricyclics is an apt one. In particular, they have similar typical side effect profiles. Tricyclics are more cardiotoxic, though, whereas opioids cause more respiratory depression. (Either can be lethal in overdose.)

> Coke gets you high? Makes me feel like shit.

I've never had any interest in it. It sounds like a horrible drug. A milder, longer-lasting, truly nonselective monoamine reuptake inhibitor might be a positive thing, though, if such a drug were available.

-elizabeth


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URL: http://www.dr-bob.org/babble/20010515/msgs/63532.html